| Test |
Monograph |
Limits |
Typical Lot Analysis |
| Assay (corrected for water), min |
ACS |
NLT 99.5% |
99.8% |
| Assay (anhydrous basis), min |
NF |
NLT 99.0% |
99.9% |
| Appearance |
ACS |
Clear liquid w/characteristic odor |
Pass |
| Appearance of solution |
BP/EP |
Clear colorless liquid |
Pass |
| Identification test A(IR) |
NF |
Conforms to infrared spectra |
Pass |
| Identification test B(GC) |
NF |
Conforms to Reference Chromatogram |
Pass |
| Specific Gravity @ 25°C, max |
NF |
NMT 0.7890 |
0.7870 |
| Identification A- relative density |
EP/BP |
0.790 – 0.793@ 20°C |
0.792 |
| Identification B |
EP/BP |
Intense red color is produced, becomes violet |
Pass |
| Identification C |
EP/BP |
A greenish-blue color is produced |
Pass |
| Color (APHA), max |
ACS |
10 |
1 |
| Residue After Evaporation, max |
ACS |
0.001% |
<0.001% |
| Residue After Evaporation, max |
BP/EP |
50ppm |
<5ppm |
| Non-Volatile Residue, max |
NF |
NMT 2mg/50mL (0.004%) |
0.3mg |
| Substances Reducing Permanganate |
ACS |
To Pass Test |
Pass |
| Readily Oxidizable Substances |
NF |
To Pass Test |
Pass |
| Reducing Substances |
BP/EP |
To Pass Test |
Pass |
| Solubility In Water |
ACS |
Solution remains clear for 30min. |
Pass |
| Matter Insoluble In Water |
BP/EP |
Solution is clear |
Pass |
| Titrable Acid, max |
ACS |
0.0003meq/g |
0.0002meq/g |
| Titrable Base, max |
ACS |
0.0006meq/g |
0.0001meq/g |
| Aldehyde (as HCHO), max |
ACS |
0.002% |
<0.002% |
| Acidity or Alkalinity |
BP/EP |
To Pass Test |
Pass |
| Methanol, max |
ACS |
0.05% |
<0.04% |
| Water, max |
ACS/NF |
0.5% |
0.20% |
| Water, max |
BP/EP |
NMT 3g/L |
2g/L |
| Isopropyl Alcohol, max |
ACS |
0.05% |
<0.0001% |
| Related Substances (by GC) |
| Impurity A- Methanol |
BP/EP |
NMT 0.05% (v/v) |
<0.004% |
| Impurity B- Isopropanol |
BP/EP |
NMT 0.05% (v/v) |
<0.0001% |
| Impurity C- Benzene |
BP/EP |
NMT 2ppm (v/v) |
<1ppm |
| Any other impurity |
BP/EP |
NMT 0.05% (v/v) |
<0.01% |