Empore™ SPE Extraction Disk Cartridges, Octadecyl (C18) and Octyl (C8)
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empore™ spe extraction disk cartridges, octadecyl (c18) and octyl (c8)
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Empore™ SPE Extraction Disk Cartridges, Octadecyl (C18) and Octyl (C8)
Cartridges
Empore™ High Performance Extraction Disk Cartridges provide an innovative alternative to packed column technology. Standard density (SD) membranes for all silica based sorbent chemistries allow reliable sample preparation for difficult sample matrices. The high density (HD) membrane formulation is intended for minimal elution volumes. Empore membranes efficiently extract samples with no channeling. The small bed volume allows compound elution from Empore cartridges in as little as 100 – 300 µL of mobile phase or mobile phase compatible solutions. Efficient extraction followed by direct injection of these solutions eliminates the need for time-consuming sample dry-down and reconstitution.
Sorbent Information
Bonded silica sorbents are commonly used for the solid phase extraction of analytes from complex matrices. Functional groups, such as octyl (C8) and octadecyl (C18), can be bonded to the silica surface to provide non polar interactions. Each of these sorbents exhibits unique properties of retention and selectivity for a particular analyte. The choice of which sorbent is best for a particular method will be influenced by the percent recovery of analyte from the sample matrix and the cleanliness of the resulting chromatography.
Empore™ C8 and C18 Extraction Disk Cartridges
Bonded silica sorbents are commonly used for the solid phase extraction of analytes from complex sample matrices. These products are intended for use during scientific research only and are not intended for use in medical devices or in assessment and treatment of clinical patients.
Features and Benefits
- Functional groups, such as octyl (C8) and octadecyl (C18), can be bonded to the silica surface to provide non polar interactions
- Each of these sorbents exhibits unique properties of retention and selectivity for a particular analyte
- The choice of which sorbent is best for a particular method will be influenced by the percent recovery of analyte from the sample matrix and the cleanliness of the resulting chromatography
Specifications
| |
C18 |
C8 |
| Bonded Functional Group |
Octadecyl |
Octyl |
| Retention Mechanism |
Strongly non polar |
Moderately non polar |
| Endcapped |
Yes |
Yes |
| Percent Carbon (avg.) |
18% |
12% |
| Pore Size (avg.) |
60 Å |
60 Å |
Applications
| Opiates |
Antidepressants |
| THC |
Benzodiazepines |
| Antibiotics |
Corticosteroids |
| Bronchodilators |
Anticonvulsants |
| Pesticides |
Peptides |
| Hypnotics |
Antihypertensives |
| Antiarrhythmics |
Analgesics |
| Vasodilators |
Immunomodulators |
Product Usage
The versatile Empore™ C8 and C18 products allow for use in the following applications
- The small bed volume and sorbent mass within Empore Extraction Disk Cartridges and 96-Well Solid Phase Extraction Plates allow for the use of reduced solvent volumes and result in more concentrated eluates
- In HPLC methods, the ability to direct inject is now possible when the eluate is compatible with mobile phase
- Time-consuming evaporation and reconstitution steps may be eliminated
- Recoveries may be improved by avoiding analyte thermal instability problems associated with an evaporation step