Empore™ SPE Extraction Disk Cartridges, type SDB-XC
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Empore™ SPE Extraction Disk Cartridges, type SDB-XC
Cartridges
Empore™ High Performance Extraction Disk Cartridges provide an innovative alternative to packed column technology. Standard density (SD) membranes for all silica based sorbent chemistries allow reliable sample preparation for difficult sample matrices. The high density (HD) membrane formulation is intended for minimal elution volumes. Empore membranes efficiently extract samples with no channeling. The small bed volume allows compound elution from Empore cartridges in as little as 100 – 300µL of mobile phase or mobile phase compatible solutions. Efficient extraction followed by direct injection of these solutions eliminates the need for time-consuming sample dry-down and reconstitution.
Sorbent Information
SDB-XC is a poly(styrenedivinylbenzene) copolymer used as a reversed phase sorbent for solid phase extraction. SDB-XC is not bonded to silica but is a 100% copolymeric particle that is spherical, porous and cross-linked. It does not exhibit the secondary cationic (silanol) interactions and pH limitations common to bonded silica sorbents, so it offers more predictable and reproducible reversed phase interaction.
SDB-XC may be substituted into methods that use C18 or C8 bonded silica and often demonstrates greater capacity. The structure of SDB-XC provides unique selectivity, especially in the retention of moderately polar, water-soluble analytes. However, since SDB-XC displays both aromatic and aliphatic interactions and does not display secondary cationic attraction, some existing methods may require adjustment to optimize analyte retention and elution.
Empore™ SDB-XC Extraction Disk Cartridges
poly(styrenedivinylbenzene) copolymer. These products are intended for use during scientific research only and are not intended for use in medical devices or in assessment and treatment of clinical patients.
Features and Benefits
- SDB-XC is a poly(styrenedivinylbenzene) copolymer used as a reversed phase sorbent for solid phase extraction
- SDB-XC is not bonded to silica but is a 100% copolymeric particle that is spherical, porous and cross-linked
- It does not exhibit the secondary cationic (silanol) interactions and pH limitations common to bonded silica sorbents, so it offers more predictable and reproducible reversed phase interaction
Comparison of Typical Silica and Copolymer Sorbents
|
Silica |
Copolymer |
pH Stability |
2 to 12 |
1 to 14 |
% Organic |
<22%* |
100% |
Secondary Interactions |
Yes |
No |
Functionality |
Aliphatic |
Aromatic and aliphatic |
Particle Shape |
Irregular |
Spherical |
Pore Size |
60 Å |
80 Å |
*varies from about 6% to 22% carbon, depending on functional group attached
Bioanalytical Applications
- glucuronide metabolites
- opiates
- stimulants
- antidepressants
- antiarrhythmics
- anticonvulsants
- antibiotics
- antihypertensives
- benzodiazepines
- moderately polar, water-soluble analytes
EPA Approved Methods
- 515.2 Chlorinated Acids
- 526.1 Selected Semi-Volatile Organics
- 8041 Phenols
- 8081 Organochlorine Pesticide Leachate
- 8270 Semi-Volatile Organic Compounds – TCLP Leachate
- 8321 Phenoxyacid Herbicides – TCLP Leachate
- 8330 Nitroaromatics and Nitroamines
Nominal Sorbent Properties
Sorbent |
Poly(styrenedivinylbenzene) |
Surface Area |
450 m2/g |
Particle Size |
16µm |
Pore Size |
80 Å |