Empore™ SPE Extraction Disks, type SDB-RPS
You have not viewed any products recently.
View Larger
- There are no alternate images available for this product.
- There are no alternate images available for this product.
Empore™ SPE Extraction Disks, type SDB-RPS
Disks
Empore™ extraction disks provide a sample prep solution for large volume samples. The disk format provides a large surface area for sorbent/sample contact. Faster flow rates and higher throughput are realized compared to liquid-liquid extraction or traditional packed column technology.
Sorbent Information
SDB-RPS is a poly(styrenedivinylbenzene) copolymer that has been modified with sulfonic acid groups to make it hydrophilic. SDB-RPS is not bonded to silica but is a 100% copolymeric particle that is spherical, porous and cross-linked. The sulfonation imparts unique selectivity for organic analytes that are polar in nature, such as drugs, drug metabolites, water-soluble pesticides and pesticide metabolites. SDB-RPS is also useful for comprehensive drug screening, in which a wide range of analytes are simultaneously extracted. Although SDB-RPS is sulfonated, it has much lower capacity than a typical strong cation exchanger. Because SDB-RPS displays reversed phase and cation exchange interactions, both functionalities can be considered for designing selective extractions. SDB-RPS can be used as a reversed phase sorbent and substituted into existing methods. Organic analytes with polar character have been shown to extract better on SDB-RPS than on traditional C18 bonded silica. However, new dimensions in selectivity and elution can be achieved by considering the influence of the sulfonic acid groups to provide some cation exchange affinity for amine-containing analytes.
Empore™ SDB-RPS Extraction Disk
poly(styrenedivinylbenzene) copolymer
These products are intended for use during scientific research only and are not intended for use in medical devices or in assessment and treatment of clinical patients.
Features and Benefits
- SDB-RPS is a poly(styrenedivinylbenzene) copolymer that has been modified with sulfonic acid groups to make it hydrophilic.
- SDB-RPS is not bonded to silica but is a 100% copolymeric particle that is spherical, porous and cross-linked
- The sulfonation imparts unique selectivity for organic analytes that are polar in nature, such as drugs, drug metabolites, water-soluble pesticides and pesticide metabolites
- SDB-RPS is also useful for comprehensive drug screening, in which a wide range of analytes are simultaneously extracted
- SDB-RPS can be used as a reversed phase sorbent and substituted into existing methods
- Organic analytes with polar character have been shown to extract better on SDB-RPS than on traditional C18 bonded silica
- Ultra-fast flow rate at 350mL/min– 2X faster than other leading brands
- Least elution volume– 1/3 of other leading brands and 1/10 of loose-packed SPE
- Highest consistency & reproducibility– 10-15% higher than Waters Oasis plates
- Least particle fines in eluates-1/10 of other leading brands to increase efficiency >25 (reducing tube clogging & system downtime
Comparison of Typical Silica and Copolymer Sorbents
| |
Silica |
Copolymer |
| pH Stability |
2 to 12 |
1 to 14 |
| % Organic |
<22%* |
100% |
| Secondary Interactions |
Yes |
No |
| Functionality |
Aliphatic |
Aromatic and aliphatic |
| Particle Shape |
Irregular |
Spherical |
| Pore Size |
60 Å |
80 Å |
*varies from about 6% to 22% carbon, depending on functional group attached
Applications
- drugs and metabolites
- pesticides and metabolites
- drugs of abuse
- explosives
- polar organic compounds
- amine-containing analytes
Nominal Sorbent Properties
| Sorbent |
Poly(styrenedivinylbenzene) sulfonated |
| Surface Area |
450 m2/g |
| Particle Size |
16 µm |
| Pore Size |
80 Å |